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General inspection of a role performed in the cell by RNAs allows us to distinguish three major groups of transcripts: I . protein-coding mRNAs, II . non-coding housekeeping and III . regulatory RNAs.
The housekeeping RNAs include RNA classes that are generally, constitutively expressed and whose presence is required for normal function and viability of the cells. On the other hand, a group of regulatory RNAs includes RNA species that are expressed at certain stages of organism development or cell differentiation or as a response to external stimuli and can affect expression of other genes on the levels of transcription or translation.
Non-coding RNA transcripts form a heterogeneous class of RNAs that can not be characterized by a single specific function. Initially, the term non-coding RNA (ncRNA) was used primarily to describe polyadenylated and a capped eukaryotic RNAs transcribed by RNA polymerase II, but lacking long open reading frames. Now, this definition can be extended to cover all RNA transcripts that do not show protein-coding capacity and is sometimes used to describe any RNA that does not encode protein, including introns.
This book is an in-depth look at the function of Non-Coding RNAs and their relationship to Molecular Biology and Molecular Biology.
Produkteigenschaften
- Artikelnummer: 9781441934086
- Medium: Buch
- ISBN: 978-1-4419-3408-6
- Verlag: Springer
- Erscheinungstermin: 30.09.2011
- Sprache(n): Englisch
- Auflage: 1. Auflage. Softcover version of original hardcover Auflage 2003
- Produktform: Kartoniert, Paperback
- Gewicht: 427 g
- Seiten: 292
- Format (B x H x T): 152 x 229 x 16 mm
- Ausgabetyp: Kein, Unbekannt
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