Literature-based Discovery

Contemporary Scienti?c Practice. 13 NeilR. SmalheiserandVetleI. Torvik The Tip of the Iceberg: The Quest for Innovation at the Base of the Pyramid. 23 M. D. GordonandN. F. Awad The ‘Open Discovery’ Challenge. 39 JonathanD. Wren Where is the Discovery in Literature-Based Discovery?. 57 R. N. Kostoff Part II Methodology and Applications Analyzing LBD Methods using a General Framework. 75 A. K. Sehgal,X. Y. Qiu,andP. Srinivasan Evaluation of Literature-Based Discovery Systems. 101 M. Yetisgen-YildizandW. Pratt vii viii Contents Factor Analytic Approach to Transitive Text Mining using Medline Descriptors. 115 J. StegmannandG. Grohmann Literature-Based Knowledge Discovery using Natural Language Processing. 133 D. Hristovski,C. Friedman,T. C. Rind?esch,andB. Peterlin Information Retrieval in Literature-Based Discovery. 153 W. Hersh Biomedical Application of Knowledge Discovery. 173 A. Koike Index. 193 Contributors NeveenFaragAwad SchoolofBusiness,WayneStateUniversity,USA CarolFriedman DepartmentofBiomedicalInformatics,ColumbiaUniversity,622West168St, NewYork,NY10032,USA MichaelD. Gordon RossSchoolofBusiness,UniversityofMichigan,USA mdgordon@umich. edu GuenterGrohmann Charite-Institute ´ ofMedicalInformatics,12203Berlin,Germany guenter. grohmann@charite. de WilliamHersh DepartmentofMedicalInformaticsandClinicalEpidemiology, SchoolofMedicine,OregonHealthandScienceUniversity, 3181SWSamJacksonParkRd. ,Portland,OR97239,USA hersh@ohsu. edu DimitarHristovski InstituteofBiomedicalInformatics,MedicalFaculty,UniversityofLjubljana, Vrazovtrg2/2,1104Ljubljana,Slovenia dimitar. hristovski@mf. uni-lj. si AsakoKoike CentralResearchLaboratory,HitachiLtd.