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Capsoni

Nerve Growth Factor

From Neuron Development to Neurology

Medium: Buch
ISBN: 978-0-443-33088-9
Verlag: Elsevier Science
Erscheinungstermin: 20.11.2026
vorbestellbar, Erscheinungstermin ca. November 2026

Nerve growth factor: From Neuron Development to Neurology, the latest release in the Molecular Mediators in Health and Disease series, offers a complete guide to nerve growth factor (NGF) across health and disease. Sections cover key properties, the latest advances, and biomedical applications of this neuropeptide. The book begins with an introduction and historical overview of the discovery of NGF before exploring its molecular characteristics. It then covers NGF in organ function, with chapters discussing the brain, immune system, blood vessels, heart, reproductive organs, teeth, and lungs. NGF pharmacology is then considered, with a focus on NGF as a therapeutic agent.

The final section of the book covers NGF across diseases, including Alzheimer’s disease, cancer, diseases of the eye, chronic pain, and visceral disfunctions. Throughout the book, NGF is considered in the context of both mammalian and non-mammalian biology, making it an ideal reference for researchers working across the fields of cell biology, molecular biology, pharmacology, and other biomedical areas.


Produkteigenschaften


  • Artikelnummer: 9780443330889
  • Medium: Buch
  • ISBN: 978-0-443-33088-9
  • Verlag: Elsevier Science
  • Erscheinungstermin: 20.11.2026
  • Sprache(n): Englisch
  • Auflage: Erscheinungsjahr 2026
  • Produktform: Kartoniert
  • Gewicht: 450 g
  • Seiten: 480
  • Format (B x H): 191 x 235 mm
  • Ausgabetyp: Kein, Unbekannt
Autoren/Hrsg.

Herausgeber

Simona Capsoni has served as Associate Professor of Physiology at University of Ferrara and Scuola Normale Superiore since 2016. Prior to this, in 2010 she joined the Bio@SNS Laboratory of Biology at Scuola Normale Superiore in Pisa (Italy) as contract junior professor where she discovered that NGF and hNGFp can affect the pathophysiology of glial cells, in particular microglia. At the same time, she started the line of research on NGF signalling system in painlessness diseases. She has published numerous papers and her primary research area focuses on the therapeutic application of hNGFp.

Part I - Introduction to Nerve Growth
1. History of Nerve Growth
2. Nerve Growth Factor in Normal Biology

Part II - Molecular biology of Nerve Growth
3. Production and structure of Nerve Growth
4. Measurement of Nerve Growth Factor and its precursor
5. Nerve Growth Factor receptors

Part III - Nerve Growth Factor in organ function
6. NGF in sensory and sympathetic neurons
7. NGF in Brain
8. NGF and the immune system
9. NGF in blood vessels and heart
10. NGF in reproductive organs
11. NGF in teeth
12. Nerve Growth Factor and the Lung.

Part IV - Nerve Growth Factor pharmacology
13. TrkA mimetics
14. P75NTR receptor blockers
15. Antibodies neutralizing NGF or TrkA
16. Nerve Growth Factor protein as a therapeutic agent

Part V - NGF in non-mammalian biology
17. NGF in non-mammalian organisms

Part VI - Nerve Growth Factor in Disease
18. Nerve Growth Factor and Alzheimer’s disease
19. Nerve Growth Factor and diseases of the eye
20. Nerve Growth factor and cancer
21. Nerve Growth Factor and chronic pain
22. Nerve Growth Factor and visceral disfunctions