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Wir sind gerne für Sie daThis work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.
Produkteigenschaften
- Artikelnummer: 9783319538679
- Medium: Buch
- ISBN: 978-3-319-53867-9
- Verlag: Springer
- Erscheinungstermin: 08.06.2017
- Sprache(n): Englisch
- Auflage: 1. Auflage 2017
- Serie: SpringerBriefs in Computer Science
- Produktform: Kartoniert, Paperback
- Gewicht: 1766 g
- Seiten: 87
- Format (B x H x T): 155 x 235 x 6 mm
- Ausgabetyp: Kein, Unbekannt