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Ebnesajjad / Ashter

Applications of Fluoropolymers in Medical Devices

Medium: Buch
ISBN: 978-0-443-21921-4
Verlag: Elsevier Science & Technology
Erscheinungstermin: 01.05.2025
vorbestellbar, Erscheinungstermin ca. Mai 2025

Fluorinated polymers have exceptional properties such as chemical resistance, neutral surfaces, modest mechanical properties, low coefficient of friction, resistance to flex fatigue and excellent performance at extreme high and low temperatures. Owing to these properties, fluoropolymers have been widely used in biomedical applications. Applications of Fluoropolymers in Medical Devices provides practical and comprehensive information on the structure, characteristics, properties, and processing methods of fluoropolymers commonly used for biomedical applications, along with a thorough description of several different medical devices containing fluoropolymers. The first part of this book describes material biocompatibility and fluoropolymers used in medical devices. Fluoropolymer types, properties and processing of parts, shapes, coatings and PTFE, such as microporous membrane and ePTFE, are discussed. The second part describes important devices containing fluoropolymers, and include a detailed overview of the design, fabrication methods, applications, and competitive materials of these devices. This book is the most authoritative reference to the subject available, and a valuable reference to scientists and engineers working in the medical device and technology areas.


Produkteigenschaften


  • Artikelnummer: 9780443219214
  • Medium: Buch
  • ISBN: 978-0-443-21921-4
  • Verlag: Elsevier Science & Technology
  • Erscheinungstermin: 01.05.2025
  • Sprache(n): Englisch
  • Auflage: Erscheinungsjahr 2025
  • Produktform: Kartoniert
  • Format (B x H): 215 x 276 mm
  • Ausgabetyp: Kein, Unbekannt
Autoren/Hrsg.

Autoren

Sina Ebnesajjad is the series editor of Plastics Design Library (PDL) published in the William Andrew imprint of Elsevier. This Series is a unique series, comprising technology and applications handbooks, data books and practical guides tailored to the needs of practitioners. Sina was the editor-in-chief of William Andrew Publishing from 2005 to 2007, which was acquired by Elsevier in 2009. He retired as a Senior Technology Associate in 2005 from the DuPont fluoropolymers after nearly 24 years of service. Sina founded of FluoroConsultants Group, LLC in 2006 where he continues to work. Sina earned his Bachelor of Science from the School of Engineering of the University of Tehran in 1976, Master of Science and PhD from the University of Michigan, Ann Arbor, all in Chemical Engineering. He is author, editor and co-author of fifteen technical and data books including five handbooks on fluoropolymers technology and applications. He is author and co-author of three books in surface preparation and adhesion of materials, two of which are in their second editions. Sina has been involved with technical writing and publishing since 1974. His experiences include fluoropolymer technologies (polytetrafluoroethylene and its copolymers) including polymerization, finishing, fabrication, product development, failure analysis, market development and technical service. Sina holds six patents.

Dr. Syed Ali Ashter is the Founder of Ashter Enterprise, LLC, a material evaluation, product development and quality compliance consulting company, which he founded in 2020. He also works as a Senior Engineering Specialist at B. Braun Medical Inc. in Irvine California. He has served on the Board of Directors for the Society of Plastics Engineer's Medical Plastics Division (MPD) since 2012. Recently, he has completed 2-year term as the chair of the Medical Plastics Division. He has authored four Plastics Engineering books in the Plastics Design Library Handbook Series.

Chapter 1 Introduction

1.1 Definition of Medical Devices

1.2 Applications of Medical Devices

1.3 Classification of Medical Devices

1.3.1 Diagnostic

1.3.2 Therapeutic

1.3.3 Implants

1.4 Medical Device Materials

1.5 Applications of Polymers in Medical Devices

Chapter 2 Biocompatibility and Regulatory Compliance

2.1 Material Biocompatibility

2.2 Assessment of Compatibility

2.2.1 Testing Strategies

2.3 Biocompatibility Test Methods

2.4 Biocompatibility of Fluoropolymers

Chapter 3 Fundamental Characteristics and Properties of Fluorinated Polymers

3.1 Uniqueness of Fluorine

3.2 Role C-F Bond in Fluoropolymers

3.3 Fluoropolymer Types: Homopolymers and Copolymers

Chapter 4 Modification of Fluoropolymer Surfaces

4.1 Perfluorinated and Partially Fluorinated Surfaces.

4.2 Methods for Surface modification of Fluoropolymers

4.3 Surface Tuning and Grafting of PTFE by Plasma Treatment

Chapter 5 Assessment of Fluoropolymers for use in Medical Devices

5.1 Introduction

5.2 Polymer characterization

5.3 Sterilization

5.4 Chemical resistance

5.5 Identification of extractable and leachable material

5.6 Biocompatibility

5.7 Shelf life and stability.

Chapter 6 Fluoropolymer Parts for Medical Devices

6.1 Microporous Membranes

6.2 Films and Sheets

6.3 Tubes (e.g. heat shrink)

6.4 Rods

6.5 Densified Films

Chapter 7 Sterilization and Disinfection of Fluoropolymer Parts

7.1 Introduction

7.2 Definitions of Sterilization and Disinfection

7.3 Commercial Sterilization Methods

7.4 Advantages/disadvantages of Sterilization Methods

Chapter 8 Introducers

8.1 Introduction to Access (access, needles, wire, catheter)

8.2 Introducer types

8.3 Micro-introducers

8.4 Peel-away introducer

8.5 Tracheal tube introducers

Chapter 9 Sutures (Sina Ebnesajjad)

9.1 Introduction and Types (PTFE, PTFE Coated)

9.2 Mono and Multi Filament

9.3 Surgical

9.4 Dental

Chapter 10 Lead Assemblies (Patents)

10.1 Introduction

10.2 Types

10.3 Cardiac Devices

Chapter 11 Catheters (Ali Ashter)

11.1 Introduction and Types

11.2 Multilumen Catheters

11.3 Guiding Catheters (active or passive manipulation)

11.4 External Catheters

11.5 MicroCatheters

11.6 Catheter Balloons

Chapter 12 Cardiovascular Devices

12.1 Vascular Implants

12.2 Covered Stents

12.3 Prosthetic Heart Valves

12.4 Vena Cava Filters

Chapter 13 ePTFE Tissue Meshes

Chapter 14 Arteriovenous ePTFE Grafts for Dialysis

14.1 Introduction and Types

14.1.1 Access

14.2 Dialysis

Chapter 15 Ligament Reconstruction and Replacement

Chapter 16 Other Devices

16.1 Coated wire

16.2 Closure Device

16.3 Microfiltration Media

16.4 PTFE Coated Electrodes

16.5 Electrosurgical blades

16.6 Forceps

16.7 Surgical (Suture) Needles

17.7.1 Tapered Needles

17.7.2 Cutting Suturing Needles

16.8 Hypodermic Needles

16.9 Mini-Vacutron

Chapter 17 Radiopacity

17.1 Introduction

17.2 Fluoroscopy and X-ray Imaging

17.3 Additives to impart Radiopacity

17.4 Applications of Radiopaque Devices

Appendix I Classification and Regulation of Medical Devices

A-1.1 FDA

A-1.2 ISO