Carolin Loos introduces two novel approaches for the analysis of single-cell data. Both approaches can be used to study cellular heterogeneity and therefore advance a holistic understanding of biological processes. The first method, ODE constrained mixture modeling, enables the identification of subpopulation structures and sources of variability in single-cell snapshot data. The second method estimates parameters of single-cell time-lapse data using approximate Bayesian computation and is able to exploit the temporal cross-correlation of the data as well as lineage information.
Produkteigenschaften
- Artikelnummer: 9783658132330
- Medium: Buch
- ISBN: 978-3-658-13233-0
- Verlag: Springer
- Erscheinungstermin: 23.03.2016
- Sprache(n): Englisch
- Auflage: 1. Auflage 2016
- Serie: BestMasters
- Produktform: Kartoniert, Paperback
- Gewicht: 1607 g
- Seiten: 92
- Format (B x H x T): 148 x 210 x 7 mm
- Ausgabetyp: Kein, Unbekannt
