Verkauf durch Sack Fachmedien

Ondra

Optimized Response-Adaptive Clinical Trials

Sequential Treatment Allocation Based on Markov Decision Problems

Medium: Buch
ISBN: 978-3-658-08343-4
Verlag: Springer
Erscheinungstermin: 18.12.2014
Lieferfrist: bis zu 10 Tage

Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences.


Produkteigenschaften


  • Artikelnummer: 9783658083434
  • Medium: Buch
  • ISBN: 978-3-658-08343-4
  • Verlag: Springer
  • Erscheinungstermin: 18.12.2014
  • Sprache(n): Englisch
  • Auflage: 2015
  • Serie: BestMasters
  • Produktform: Kartoniert, Paperback
  • Gewicht: 1657 g
  • Seiten: 102
  • Format (B x H x T): 148 x 210 x 7 mm
  • Ausgabetyp: Kein, Unbekannt
Autoren/Hrsg.

Autoren

Introduction to Markov Decision Problems and Examples.- Finite and Infinite Horizon Markov Decision Problems.- Solution Algorithms: Backward Induction, Value Iteration and Policy Iteration.- Designing Response Adaptive Clinical Trials with Markov Decision Problems.