Microbiology and Aging

Chapter7highlightsthechangesthatoccurintheoral micro?ora and host defences with advanced age with Chap. 8 reviewing the in?uenceofthegutmicrobiotawithageing. Chapter8focusesonthegutandits associatedimmunity. Theremainingfourchaptersofthebookconsiderclostridium andtheageinggut,Helicobacterpyloriandthehygienehypothesisandthebene?ts of probiotics. The microbiology theory of autism in children is reviewed in vii viii Preface Chap. 13. The?nalchapterofthebookexamineshowthebene?cialmicrobiology ofthehostleadstohumandecomposition. Thisbookencompassesacollectionofreviewsthathighlightthesigni?canceof andthecrucialrolethatmicroorganismsplayinthehumanlifecycle. Flintshire,UK StevenL. Percival Contents 1 AgeingTheories,DiseasesandMicroorganisms. 1 StevenL. Percival 2 IndigenousMicrobiotaandAssociationwiththeHost. 15 JohnG. ThomasandStevenL. Percival 3 InfectionsintheElderly. 39 KnutOhlsen,SvitlanaKozytska,andUdoLorenz 4 SkinAgingandMicrobiology. 57 LeslieBaumann,EdmundWeisberg,andStevenL. Percival 5 LungInfectionsandAging. 95 SameerK. MathurandKeithC. Meyer 6 In?uenzaintheElderly. 113 CaterinaHatzifotiandAndrewWilliamHeath 7 ChangesinOralMicro?oraandHostDefences withAdvancedAge. 131 RimondiaS. Percival 8 In?uenceoftheGutMicrobiotawithAgeing. 153 EileenMurphy,CarolineMurphy,andLiamO’Mahony 9 AGutReaction:AgingAffectsGut-AssociatedImmunity. 175 JosephF. AlbrightandJuliaW. Albright 10 ClostridiumandTheAgeingGut. 223 SarahConnorandStevenL. Percival ix x Contents 11 TheSigni?canceofHelicobacterPyloriAcquisition andtheHygieneHypothesis. 263 StevenL. Percival 12 ProbioticsandtheAgeingGut. 275 StevenL. Percival 13 MicrobiologicalTheoryofAutisminChildhood. 291 StevenL. Percival 14 DecompositionofHumanRemains. 313 RobertC. Janaway,StevenL. Percival,andAndrewS. Wilson Index. 335 Contributors JosephF. Albright,PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine,Washington,DC,USA JuliaW. Albright,PhD Departmentof Microbiology, Immunology and Tropical Medicine, The George WashingtonUniversitySchoolofMedicine,Washington,DC,USA LeslieBaumann,MD UniversityofMiamiCosmeticCenter,MiamiBeach,FL,USA SarahConnor,MSc DepartmentofMicrobiology,LeedsGeneralIn?rmary,Leeds,UK CaterinaHatzifoti,PhD UniversityofShef?eldMedicalSchool,BeechHillRoad,Shef?eld,UK AndrewW. Heath,PhD UniversityofShef?eldMedicalSchool,BeechHillRoad,Shef?eld,UK RobertC.