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Rodríguez-Ezpeleta / Hackenberg / Aransay

Bioinformatics for High Throughput Sequencing

Medium: Buch
ISBN: 978-1-4614-0781-2
Verlag: Humana
Erscheinungstermin: 25.10.2011
Lieferfrist: bis zu 10 Tage

Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein – DNA interaction sites and detection of structural variation. The generation of gigabases of sequence information for each of this huge bandwidth of applications in just a few days makes the development of bioinformatics applications for next generation sequencing data analysis as urgent as challenging.


Produkteigenschaften


  • Artikelnummer: 9781461407812
  • Medium: Buch
  • ISBN: 978-1-4614-0781-2
  • Verlag: Humana
  • Erscheinungstermin: 25.10.2011
  • Sprache(n): Englisch
  • Auflage: 2012
  • Produktform: Gebunden, HC runder Rücken kaschiert
  • Gewicht: 571 g
  • Seiten: 255
  • Format (B x H x T): 160 x 241 x 21 mm
  • Ausgabetyp: Kein, Unbekannt
Autoren/Hrsg.

Herausgeber

Preface.- Introduction.- Overview of Sequencing Technology Platforms.- Applications of High Throughput Sequencing.- Computational Infrastructure and Basic Data Analysis for High-Throughput Sequencing.- Base-Calling for Bioinformaticians.- De Novo Short Read Assembly.- Short Read Mapping.- DNA-Protein Interaction Analysis (ChIP-Seq).- Genome-wide Methylation Maps.- Differential Expression for RNA Sequencing (RNA-seq) Data: Mapping, Summarization, Statistical Analysis and Experimental Design.- MicroRNA Expression Profiling and Discovery.- Dissecting Splicing-Regulatory Network by Integrative Analysis of HITS-CLIP data.- Analysis of Metagenomics Data.- High Throughput Sequencing Data Analysis Software: Current State and Future Developments.- Index.