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Sethi / Chatterjee

Recent Advances in Targeting Inflammation

Ion channels, GPCR Signaling Tools, Therapies, and Beyond

Medium: Buch
ISBN: 978-0-443-33887-8
Verlag: Elsevier Science Publishing Co Inc
Erscheinungstermin: 10.09.2026
vorbestellbar, Erscheinungstermin ca. September 2026

Recent Advances in Targeting Inflammation: Ion Channels, GPCR Signaling Tools, Therapies, and Beyond delves into the multifaceted occurrences of inflammation across different systems, such as neuroinflammation and gastric inflammation. The book's main goal is to present the latest highlights, covering advancements in inflammation, investigational therapies, animal models, and biomarkers. These insights are crucial for better diagnosis, monitoring, and potential therapeutic options for patients suffering from both acute and chronic inflammation. This comprehensive work explores various topics, including ion channel regulation in inflammation, GPCR regulation, signaling pathways, and therapeutic approaches.

It emphasizes the importance of understanding the role of ion channels, GPCR, and nutrition in managing inflammation effectively. Additionally, the book discusses the global impact of chronic inflammation on health outcomes, stressing the need for improved healthcare planning and strategies.


Produkteigenschaften


  • Artikelnummer: 9780443338878
  • Medium: Buch
  • ISBN: 978-0-443-33887-8
  • Verlag: Elsevier Science Publishing Co Inc
  • Erscheinungstermin: 10.09.2026
  • Sprache(n): Englisch
  • Auflage: Erscheinungsjahr 2026
  • Produktform: Kartoniert
  • Gewicht: 450 g
  • Seiten: 600
  • Format (B x H): 191 x 235 mm
  • Ausgabetyp: Kein, Unbekannt
Autoren/Hrsg.

Herausgeber

Dr. Gautam Sethi is a tenured Associate Professor in the Department of Pharmacology at the Yong Loo Lin School of Medicine, National University of Singapore. His research focuses on elucidating the molecular mechanisms underlying cancer initiation and progression, particularly the activation of oncogenic transcription factors by carcinogens and inflammatory agents, and the identification of novel therapeutic inhibitors. Dr. Sethi has made substantial and direct scholarly contributions to the fields of gut microbiota, cancer pathophysiology, and host–microbiome interactions, with particular emphasis on immunotherapy, tumor microenvironment modulation, metabolic signaling, and therapy response prediction. He has authored numerous peer-reviewed research and review articles in high-impact journals, received multiple international awards, and serves on the editorial boards of more than 15 international journals.

Dr. Ankita Chatterjee is an Assistant Professor in Department of Biotechnology, School of Applied Sciences, REVA University, Bangalore, India. Her research area includes microbial technology focusing on the effect of microorganisms and microbial metabolites in reducing the environmental pollutants. The area of research also spans around extraction of pharmaceutically active bioactive compounds from natural sources and their analyses. She has 35 publications at present which include 22 research and review papers in reputed international and national journals as well as 13 book chapters in internationally edited books under reputed publishers. She has served as reviewer for various international journals.

Section 1: Introduction and Ion channels regulation in inflammation
1. Introduction : Voltage gated ion channels and GPCR signaling in inflammation
2. Calcium - dependent regulation of ion channels in inflammation
3. Unveiling the Significance of Mitochondrial Ion Channels in Inflammatory Responses
4. Neuroinflammation with regards to ion Channels dysregulation

Section 2: GPCR regulation in inflammation
5. Role of GPCRs in Inflammasome activation and Therapeutics
6. G-Protein Coupled Receptors Linked with the MASLD-MASH Transition: Updates for Pharmacotherapeutic Development
7. Molecularity of GPCR Signaling involved in Neuroinflammation
8. GPCR regulation of chemokine, lipid mediator and neuropeptide receptors in inflammation

Section 3: Signaling Pathways in Inflammation
9. G protein-coupled receptors: structure- and function-based drug discovery
10. Alteration of inflammatory Signaling network in cancer
11. Role of MAPK in Neuroinflammation: A molecular approach

Section 4: Therapeutic approaches for inflammation
12. G-protein-coupled receptors (GPCRs) in the treatment of diabetes
13. Application of Nanoparticles for Targeting G Protein-Coupled Receptors
14. Advancements in Targeting Ion Channels and GPCRs for inflammation therapy: Molecular Insights and Clinical Implications
15. Nano-therapeutic strategies for inflammation via GPCR modulation: An update
16. Innovative GPCR Targeting Strategies in Drug Therapy for Inflammatory Diseases: Mechanistic Approaches
17. Distinctive applications of nano-therapeutics in mitigating metabolic disorder-inflammation
18. Therapeutic approaches for inflammation