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Signal Detection for Medical Scientists

Likelihood Ratio Test-based Methodology

Medium: Buch
ISBN: 978-1-032-01634-4
Verlag: Chapman and Hall/CRC
Erscheinungstermin: 26.06.2023
Lieferfrist: bis zu 10 Tage

Signal Detection for Medical Scientists: Likelihood Ratio Based Test-Based Methodology presents the data mining techniques with focus on likelihood ratio test (LRT) based methods for signal detection. It emphasizes computational aspect of LRT methodology and is pertinent for first-time researchers and graduate students venturing into this interesting field.

The book is written as a reference book for professionals in pharmaceutical industry, manufactures of medical devices, and regulatory agencies. The book deals with the signal detection in drug/device evaluation, which is important in the post-market evaluation of medical products, and in the pre-market signal detection during clinical trials for monitoring procedures.

It should also appeal to academic researchers, and faculty members in mathematics, statistics, biostatistics, data science, pharmacology, engineering, epidemiology, and public health. Therefore, this book is well suited for both research and teaching.

Key Features:

- Includes a balanced discussion of art of data structure, issues in signal detection, statistical methods and analytics, and implementation of the methods

- Provides a comprehensive summary of the LRT methods for signal detection including the basic theory and extensions for varying datasets that may be large post-market data or pre-market clinical trial data

- Contains details of scientific background, statistical methods, and associated algorithms that a reader can quickly master the materials and apply methods in the book on one’s own problems


Produkteigenschaften


  • Artikelnummer: 9781032016344
  • Medium: Buch
  • ISBN: 978-1-032-01634-4
  • Verlag: Chapman and Hall/CRC
  • Erscheinungstermin: 26.06.2023
  • Sprache(n): Englisch
  • Auflage: 1. Auflage 2023
  • Serie: Chapman & Hall/CRC Biostatistics Series
  • Produktform: Kartoniert
  • Gewicht: 377 g
  • Seiten: 244
  • Format (B x H x T): 156 x 234 x 13 mm
  • Ausgabetyp: Kein, Unbekannt
Autoren/Hrsg.

Autoren

1. Introduction 2. Data Mining Methods for Signal Detection 3. Basic LRT Method 4. LRT Methods for Drug Classes 5. ZIP-LRT Method for Modeling Extra-zeros 6. LRT Method for Active Safety Surveillance with Exposure Information 7. LRT-based Methodologies for Analysis of Multiple Studies 8. LRT Methods in Medical Device Safety Evaluation 9. LRT Method for Multiple-Site Device Data with Continuous Outcomes 10. Use of LRT in Site Selection