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More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman’s famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging.
Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington’s disease, Parkinson’s disease, and traumatic brain disease in animal models of neurodegeneration.
This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.
Produkteigenschaften
- Artikelnummer: 9781466594869
- Medium: Buch
- ISBN: 978-1-4665-9486-9
- Verlag: CRC Press
- Erscheinungstermin: 27.10.2014
- Sprache(n): Englisch
- Auflage: 1. Auflage 2014
- Produktform: Gebunden
- Gewicht: 498 g
- Seiten: 259
- Format (B x H x T): 156 x 235 x 19 mm
- Ausgabetyp: Kein, Unbekannt