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Walton

Equine Clinical Pathology

Medium: Buch
ISBN: 978-0-8138-1719-4
Verlag: Iowa State University Press
Erscheinungstermin: 18.10.2013
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Equine Clinical Pathology is the first complete resource for hematology and clinical chemistry in horses. Encompassing the basic principles and advanced interpretation, the book's single-species approach to pathology allows for focused coverage of the unique disease characteristics of equids. Equine Clinical Pathology is equally useful for anyone using clinical pathology as a diagnostic tool, from beginning student to experienced specialist.

The heart of the book is organized by body system, making it easy to find and apply information. Chapters cover general laboratory medicine, including instruments and techniques, hematology, and proteins as well as specific organs, such as the kidney and liver. Equine Clinical Pathology is a useful bench-side reference for anyone involved in laboratory medicine for the horse.

Produkteigenschaften

  • Artikelnummer: 9780813817194
  • Medium: Buch
  • ISBN: 978-0-8138-1719-4
  • Verlag: Iowa State University Press
  • Erscheinungstermin: 18.10.2013
  • Sprache(n): Englisch
  • Auflage: 1. Auflage 2013
  • Produktform: Gebunden
  • Gewicht: 734 g
  • Seiten: 296
  • Format (B x H x T): 251 x 177 x 19 mm
  • Ausgabetyp: Kein, Unbekannt
  • Nachauflage: 978-1-119-50024-7

Themen

Autoren/Hrsg.

Herausgeber

Contributors xiPreface xiii1 General Laboratory Medicine 3Raquel M. WaltonGeneral laboratory medicine 3Basic hematologic techniques 4Point-of-care testing 6Test validation and reference values 10References 142 Equine Hematology 15Raquel M. WaltonComplete blood count interpretation 15Erythrocyte indices 15Leukogram 20Platelets 22Blood film evaluation 23Erythrocytes and platelets 25Leukocytes 30References 333 Immunohematology and Hemostasis 37Karen V. JacksonImmunohematology testing 39Blood typing 39Crossmatching 41Antibody screening and jaundiced foal agglutination test 42Immune-mediated hemolytic anemia 44Neonatal isoerythrolysis 46Infection-associated (Clostridial, EIA, R. equi, S. equi) 48Drug-associated 50Neoplasia-associated 50Coagulation testing 51Physiology of hemostasis 51Coagulation testing and disorders causing abnormalities 60References 664 The Liver 71Dennis J. Meyer and Raquel M. WaltonLiver enzymes 71Hepatocellular enzymes 73Hepatobiliary enzymes 74Liver function tests 76Excretory function tests 76Tests dependent on synthetic/metabolic functions 77Other tests 79Hepatic diseases 80Toxins 80Infections 82Hepatic lipidosis 83Serum hepatitis (Theiler's disease) 83Hepatocellular neoplasia 84References 845 Laboratory Evaluation of the Equine Renal System 87Andrea A. BohnLaboratory assessment of the kidney 87Glomerular filtration rate 89Reabsorption and electrolyte regulation 90Water conservation and blood volume regulation 91Other renal functions 92Urinalysis 92Gross evaluation 92Urine-specific gravity 92Reagent test strips 94Urine sediment exam 95Laboratory abnormalities associated with different disease states 98Acute renal failure 98Chronic renal failure 98Urinary tract rupture 99"Early" renal disease 100Strenuous exercise 101References 1016 Acid-Base and Electrolytes 103Andrea A. BohnAcid-base 103Steps to evaluating acid-base status 104Bicarbonate 104Metabolic acidosis and alkalosis 105Respiratory acidosis and alkalosis 106Compensatory mechanisms 106Base excess 107Electrolytes 107Sodium 107Chloride 109Potassium 110Calcium 112Magnesium 114Phosphate 115References 1167 Proteins 119Koranda WallacePlasma proteins 119Albumin 119Globulin 120Acute phase proteins 120Protein disorders 124Hypoalbuminemia with hypoglobulinemia 124Hypoalbuminemia with normal or increased globulins 125Hypoglobulinemia with normal to increased albumin 125Hyperalbuminemia 126Hyperalbuminemia and hyperglobulinemia 126Hyperglobulinemia 126Hyperfibrinogenemia 127References 1278 Laboratory Assessment of Lipid and Glucose Metabolism 131Raquel M. WaltonLipids 131Triglyceride metabolism 132Laboratory characterization of lipid metabolism 133Equine hyperlipidemias 136Glucose 138Glucose metabolism 139Insulin resistance 140Laboratory characterization of glucose metabolism 140Diseases associated with glucose metabolic defects 145References 1499 Skeletal Muscle 153Allison BillingsLaboratory evaluation of equine muscle disorders 153General causes of increased serum enzymes 153Serum enzymes detecting muscle injury 154Additional factors affecting CK and AST enzyme activity 158Other markers detecting muscle injury 159Equine muscle diseases 161Immune-mediated myopathies 161Infectious myopathies 163Traumatic myopathies 165Inherited or congenital myopathies 166Toxic myopathies 169Nutritional myopathies 171Myopathies of unknown cause 171Other myopathies 173References 17310 Endocrine Evaluation 181Jill BeechTesting for pituitary pars intermedia dysfunction (PPID) 181Cortisol concentrations 182Adrenocorticotropin (ACTH) concentration 184Alpha-melanocyte-stimulating hormone (alpha-MSH) concentrations 186ACTH and alpha-MSH concentration responses following thyrotropin releasing hormone (TRH) administration 186Insulin concentrations 187Testing thyroid function in horses 189Thyroid dysfunction 189Thyroid hormones 189Extrathyroidal effects on thyroid hormones 190Nonthyroidal illness syndrome 192Thyroid hormone evaluation 192Thyroid stimulating hormone (TSH) concentration 193Thyrotropin releasing hormone (TRH) stimulation 194TSH stimulation test 194T3 suppression test 195References 19511 Fluid Analysis 203Raquel M. WaltonPleural and peritoneal fluid 203Pathogenetic mechanisms of body cavity effusions 204Body cavity fluid analysis 208Biochemical evaluation 210Cells and cell counts 212Synovial fluid 218Fluid analysis 219Degenerative arthropathies 224Inflammatory arthropathies 225Eosinophilic synovitis 227Hemarthrosis 227References 22912 Cytology of the Lower Respiratory Tract 233Martina PivianiIndications 233Collection techniques 234Bronchoalveolar lavage 234Tracheal wash 234Sample processing 235Normal findings 236Cellular elements 236Acellular elements 239Contaminants 240Interpretation of cytologic patterns 241Neutrophilic inflammation 241Mixed neutrophilic and histiocytic inflammation 245Eosinophilic and mastocytic inflammation 245Hemosiderosis 246Cellular atypia 248References 24913 Cerebrospinal Fluid 253Andrea SiegelFormation, circulation, absorption, and function 253Collection 254Laboratory analysis 254Gross appearance 255Protein concentration 256Antibody titers 258Cell counts 258Glucose 260Enzymes 260Lactic acid 260Polymerase chain reaction 261Phenotyping 261Cytological examination 261Normal findings 262Abnormal findings 263CSF in specific diseases 264Viral infections 264Bacterial infections 265Fungal infections 265Parasitic infections 266Other diseases 266References 266Index 271