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Wir sind gerne für Sie daThis book presents a guide to building computational gene finders, and describes the state of the art in computational gene finding methods, with a focus on comparative approaches. Fully updated and expanded, this new edition examines next-generation sequencing (NGS) technology. The book also discusses conditional random fields, enhancing the broad coverage of topics spanning probability theory, statistics, information theory, optimization theory and numerical analysis. Features: introduces the fundamental terms and concepts in the field; discusses algorithms for single-species gene finding, and approaches to pairwise and multiple sequence alignments, then describes how the strengths in both areas can be combined to improve the accuracy of gene finding; explores the gene features most commonly captured by a computational gene model, and explains the basics of parameter training; illustrates how to implement a comparative gene finder; examines NGS techniques and how to build a genome annotation pipeline.
Produkteigenschaften
- Artikelnummer: 9781447166924
- Medium: Buch
- ISBN: 978-1-4471-6692-4
- Verlag: Springer
- Erscheinungstermin: 22.04.2015
- Sprache(n): Englisch
- Auflage: 2. Auflage 2015
- Serie: Computational Biology
- Produktform: Gebunden, HC runder Rücken kaschiert
- Gewicht: 7273 g
- Seiten: 382
- Format (B x H x T): 160 x 241 x 28 mm
- Ausgabetyp: Kein, Unbekannt
- Vorauflage: 978-1-84996-103-5