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Wir sind gerne für Sie daThis book presents a guide to building computational gene finders, and describes the state of the art in computational gene finding methods, with a focus on comparative approaches. Fully updated and expanded, this new edition examines next-generation sequencing (NGS) technology. The book also discusses conditional random fields, enhancing the broad coverage of topics spanning probability theory, statistics, information theory, optimization theory and numerical analysis. Features: introduces the fundamental terms and concepts in the field; discusses algorithms for single-species gene finding, and approaches to pairwise and multiple sequence alignments, then describes how the strengths in both areas can be combined to improve the accuracy of gene finding; explores the gene features most commonly captured by a computational gene model, and explains the basics of parameter training; illustrates how to implement a comparative gene finder; examines NGS techniques and how to build a genome annotation pipeline.
Produkteigenschaften
- Artikelnummer: 9781447168751
- Medium: Buch
- ISBN: 978-1-4471-6875-1
- Verlag: Springer
- Erscheinungstermin: 05.10.2016
- Sprache(n): Englisch
- Auflage: Softcover Nachdruck of the original 2. Auflage 2015
- Serie: Computational Biology
- Produktform: Kartoniert, Paperback
- Gewicht: 6088 g
- Seiten: 382
- Format (B x H x T): 155 x 235 x 22 mm
- Ausgabetyp: Kein, Unbekannt